Preclinical Trial Services

It enhances our capacity for single-source efficiencies and as an “end-to-end” service provider— from target evaluation through preclinical ...

Similarly, our state-of-the-art technology centre can accommodate development and production of bespoke recombinant albumin suitable for use in discovery through to preclinical ...

Capability to test our manufactured products in vivo in swine ...

We offer regulatory consulting services to support our member organizations with preclinical study design, FDA submissions and interactions and clinical trial design to support existing industries and grow new ones. ...

Alesi Surgical and WIMAT are co-located and collaborate on research and development, testing, product design, pre-clinical evaluation and post-market clinical follow-up. This provides a unique level of access to experienced surgeons, surgical trainers and trainees, and ...

It covers an extensive spectrum of pharmaceutical expertise and the ability to design and carry out precise and ad hoc assessments in the discovery and development of new therapies.Drawing on our experience and expertise in the preclinical investigation of new therapeutic entities – with different mechanisms of action – in various indications, and given our mastery of ...

To overcome the weaknesses and limitations of current cell-based and animal-based testing, 3D models with the appropriate biophysical tissue architecture are generated for cardio-toxicity test in order to provide highly predictive and detailed information for the human in vivo study. Creative Bioarray offers the opportunity for highly predictable pre-clinical cardio-toxicity testing to help our ...

Solvias is a highly experienced resource for your chemical development needs, from pre-clinical support and process research and development to kg-scale synthesis. When it comes to chemical development and manufacturing, you can rely on our proven expertise ...

The objective of the Hepatitis B virus (HBV) Program is to utilize the HOOKIPA Technologies to design arenavirus vectors (Lymphocytic Choriomeningitis Virus or Pichinde Virus based) suitable for treatment, cure or prevention of HBV. Together with our partner Gilead Sciences we intend to develop functional therapies for patients already infected with ...

Our experimental studies strictly follow ICH, CFDA, FDA and OECD guidelines, providing our clients with high quality data and fast study cycles for preclinical safety evaluation of drugs. alfa chemistry helps our clients to shorten the experimental time and reduce the cost of new drug development through cost control and efficient ...

Champions Oncology has created screens that enroll each month in either In vivo, Ex Vivo or In vitro platforms. These screens allow for a significant cost savings compared to running stand-alone studies as well as provide free access to Standard of Care response data and other characterization data for each model. Check back frequently to learn more about each screen and to enroll in any active ...

Scientific knowledge, distilled and delivered. We combine artificial intelligence and a multi-disciplinary research team to get insights across all stages of development. From early drug discovery and pre-clinical studies to post-marketing surveillance. ...

Our more than 50 R&D experts can rapidly develop scalable, robust and cost-effective chemical processes and optimize reaction conditions for your complex, often chiral, intermediates or APIs. Our processes can be readily transferred to our kilo lab in the form of a proof of concept study, or for scale-up and delivery of material to support your pre-clinical studies. We can also enable you to ...

The Pharmacovigilance system collects and studies adverse events (=noxious) which may be associated to a drug treatment, in order to assess their incidence. identify the cause-effect relationship with the use of the drug. identify any possible risk factors for the occurrence of such adverse events. identify possible means for the prevention of such adverse ...

Rodent disease models are widely used for a broad range of project objectives, which involve investigation of pathological process and mechanism of disease, pre-clinical tests of potential therapeutic agents, ...

Prior to clinical trials, it is necessary to conduct animal toxicity studies to best characterize the potential toxicity of new drug candidates. Generally, the objective of preclinical safety evaluation is to determine the toxic effects with respect to target organs, dose dependency, the relationship between clinical findings and exposure to the compound, and ...

A more seamless transition into the clinic. Complex biopharmaceuticals and advanced therapies can present challenges during preclinical development. When implementing an albumin-based solution, Albumedix can help avoid unnecessary complications in your preclinical testing by creating species-specific recombinant albumins to suit your preclinical ...

In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical pharmacology and safety studies. In vivo PK studies provide required and useful information that indicates human equivalent doses (HED), no effect levels (NOEL), and pharmacokinetic/pharmacodynamic (PK/PD) drivers. Conducting PK studies also allows the ...

Agile and flexible to accelerate value creation. Jubilant Therapeutics is open for partnering or strategic. collaborations with biotech, pharma, academia, research labs for: Accelerating clinical development and market launch of our ongoing programs. Discovery/development of new programs in synergistic areas. Conducting research with our drug candidates either as monotherapy or in combination to ...

Using our platform, we have uncovered novel therapeutic RNAi approaches that aid heart cell regeneration and proliferation. Patents, publications in progress; compounds validated in preclinical ...