Neurodegenerative Disease Services

Neurodegenerative diseases (NDs) comprise a diverse set of pathological processes involving progressive neuronal dysfunction, degeneration, and death, leading to incurable and debilitating diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in neurodegeneration-related mitochondria ...

Creative Biogene provides the fractionated mitochondrial magnetic separation (FMMS) method to increase the production of brain-derived mitochondria compared with the UC method and can better detect mitochondrial damage in the central nervous system injury and neurodegenerative ...

Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of human MS as it is especially useful to investigate neuroinflammatory pathways and often serves as a "proof-of-principle" model for the efficacy of novel treatment ...

Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as ...

To keep up its high level of Competitiveness, Neuron Experts constantly develops new cellular models to provide the most accurate answers to customers’ needs: Development of new neurodegenerative disease models following current discoveries of new therapeutic targets, Development of new cellular models to study interaction between neurons and skin, ...

"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary ...

PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...

PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative diseases, but also provide a unique chemical knockdown tool for biological research in a catalytic, ...

Biomarker specializations include Alzheimer’s and dementia, Parkinson’s and basal ganglia disorders, mood disorders and other neurodegenerative and neuropsychiatric diseases. ...

Bacterial translocation: the missing link between intestinal microbiome and human complex non-communicable diseases. Complex disorders are multifactorial and often chronic, caused by genetic and environmental factors and comprising hundreds of conditions from cardio-metabolic diseases to neurodegenerative and mental disorders. These pathologies ...

The Neuron Experts team (operational and scientific) provides support and advice in your R&D programs and also in the development of new molecules in specific disease indications. ...

During ReGen’s discussions with potential licensing partners in 2004, it became apparent that a product based on the Colostrinin™ complex, as a whole, was more commercially attractive as a nutraceutical, rather than as a pharmaceutical. It was decided, therefore, to develop the original formulation of Colostrinin™ as a ...

Neuroscience solutions that improve the quality of life. We specialize in the development of innovative solutions in the field of therapy and research of the brain and the central nervous system. We create neurostimulation methods, that solve unmet medical needs and improve the quality of human life. We create an image of modern ...

Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...

SAM analog and antibody: One of the important S-adenosylmethionine (SAM) analogs has a very good thermostability and yet a high hygroscopicity. This analog can also be used as a standard in in intro assays of ...

Cerebrospinal fluid (CSF) is secreted within the central nervous system (CNS) and fills in the ventricles, the subarachnoid space of the brain, and the spinal column. CSF's role is to protect the brain from physical impacts. Furthermore, CSF plays a crucial role in the circulation of nutrients and chemicals in the blood and in waste management by actively transporting or facilitating bulk flow ...