Symberix, Inc.

Symberix, Inc.

- Microbiome Drugs

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A microbiome is a collection of microorganisms (and their DNA) that occupy a particular location. The 'human microbiome' is composed of trillions of tiny microbes (mostly bacteria) that thrive in our mouth, on our skin, and inside our gut. An individual's gut microbiome is a unique and diverse community of thousands of distinct bacterial species. The vast majority of these bacteria are not harmful - in fact, many are essential to human health. In recent years, the human microbiome has been identified as an essential complement to the human body. Although gut bacteria make a positive contribution to our overall health, they have also been linked to negative health outcomes and illnesses.

How can we influence our mkrobiome?

How can we influence our mkrobiome?

Since the 1940s, antibiotics have been used to treat bacteria-related illness. Antibiotic drugs revolutionized modern medicine with their ability to destroy bad bacteria by lethally targeting entire bacterial populations. Despite their clinical importance, the overuse of antibiotics has put pressure on bacteria to evolve resistance, causing a rapid emergence of antibiotic-resistant infections.

Unfortunately, antibiotics also kill neutral (“commensal”) and beneficial bacteria that reside in the human gut. As pioneers of precision microbiome medicine, Symberix is developing a portfolio of small molecule drugs that selectively eliminate harmful bacterial activity without killing the good bacteria or contributing to antibiotic resistance. Learn more about these 'symbiotic drugs' here.

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