Monoclonal Antibody Equipment & Supplies

Polyclonal Antibody to detect 14-3-3 in Human, Mouse, Rat, pig, monkey, rabbit, dog, sheep and bovine samples. The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. ...

Glunomab / Glunozumab®: a monoclonal antibody counteracting the strong toxicity triggered by the interaction of an endogenous protease, tissue plasminogen activator (tPA) with NMDA receptors ...

PMC-402 is a monoclonal antibody that targets the human TIE2 that regulated activation, proliferation, and repolarization of Tie2 expressing macrophages, resulting in T cell activation. It binds to TIE2 expressing macrophages that activate T cells in the tumor microenvironment ...

The first monoclonal antibody was generated in mice in 1975 by Milstein and Kohler, using the hybridoma technique. ...

A monoclonal antibody against insulin-like growth factor-1 receptor (IGF-1R). TED in Japan (OPTIC-J): Phase 3 randomized, placebo-controlled trial in Japan to evaluate TEPEZZA in patients with moderate-to-severe active ...

PMC-403 is a monoclonal antibody that targets the human TIE2 that regulate the angiogenesis and vessel maturation in endothelial cells. It binds to TIE2 expressing endothelial cells and normalize VEGF-induced pathological leaky blood vessels in eyes and TME (tumor ...

Intended use: Test cards for ABO identity checking before blood ...

Rapid Prime identifies positive monoclonal antibodies in as little as 32 days. This method is especially beneficial for generating anti-idiotypic antibodies, and producing monoclonal antibodies against conformational epitopes. Other sources of immunogens include conserved or smaller proteins, peptides, and whole ...

Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Aliquot and store at -20°C to -80°C. ...

The Mouse FYN mAb (APAT1005) is produced in mouse using recombinant protein of human FYN as the immunogen. This antibody is suitable for immunoassay applications and may cross-react with other ...

The clone L243, a mouse monoclonal antibody, recognizes a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain known as human HLA-DR antigen. HLA-DR is widely expressed on monocytes, macrophages, activated T and B lymphocytes, activated natural killer (NK) cells, and human progenitor cells. ...

Storage: Store at -20°C to -80°C, avoid repeat freeze- thaw; Manufacturer Country: USA; Buffer: 0.15M PBS; Disease Area: Hormones; Purity/grade: determined by size-exclusion chromatography; Applications: ELISA; Clone Number: 19G11; Immunogen / Epitope: ...

Monoclonal antibodies (mAbs) are the largest segment of marketed biopharmaceuticals today. Whether you are developing an originator molecule or a biosimilar, your antibody derived from a recombinant cell line such as Chinese Hamster Ovary (CHO) must meet regulatory standards for the absence of virus and other ...

The clone M-­2E6, a mouse monoclonal antibody selectively recognizes the epitope present in the Fab arms (anti- Fdµ) of the surface monomeric IgM molecule on B cells. It reduces the growth of the neoplastic B cells through its intrinsic crosslinking property in vitro. ...

PMC-309 is an engineered monoclonal antibody that targets the negative immune checkpoint human VISTA (V-domain Ig suppressor of T cell activation). It indirectly promotes T cells' immune responses by inhibiting VISTA-expressing immunosuppressive cells such as MDSCs (Myeloid-Derived Suppressor Cells) which suppress T cell inactivation and ...

BOS-371 is a highly potent monoclonal antibody targeting the Interleukin-1 Receptor Accessory Protein (IL1RAP), a prevalent tumor associated antigen driving tumor growth and immunosuppression. BOS-371 has also been Fc-engineered to enhance effector ...

At this point, you have identified a mouse monoclonal antibody that will be of use to your research and/or product development and you need more of it produced - what are the next steps? While it will depend on your specific needs, in general we will recommend doing two additional subclonings (one subclone becomes a master bank of hybridoma cells and a second ...

The Rabbit STIP1 mAb (APAT1003) is produced in rabbit using a synthesized peptide derived from human STIP1 as the immunogen. This antibody is suitable for immunoassay applications and may cross-react with other ...

Shipping Information: Supply of these antibodies is subject to export control restrictions; Abbreviations: Burkholderia; Storage: Store at -20°C, avoid repeat freeze- thaw cycles; Manufacturer Country: UK; Buffer: Phosphate buffered saline pH 7.2; Disease Area: Infectious Disease; Applications: Academic,Elisa, Lateral Flow; Clone Number: BBI159; Host: Mouse; Isotype: ...

Ofatumumab is a human monoclonal antibody which targets an epitope in the CD20 molecule encompassing parts of the small and large extracellular ...