In Vivo Studies Equipment & Supplies

Precision Approach to Address the Underlying Cause of Disease: Our second candidate, MuSK-CAART, is designed to treat myasthenia gravis (MG), an autoimmune disease affecting the neuromuscular junction that can lead to motor impairment, muscle weakness, and respiratory ...

A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...

Data Driven Performance - In Vivo Study Results; Bioactive glass has typically been used in a particulate form consisting of irregular particles and a broad size range (32-710 um). Instead of creating a bone graft with these "off-the-shelf" particles, Synergy utilized a unique spherical particle shape and conducted an in vivo optimization ...

Embedded ALPINION’s proprietary HIFU technology and imaging technologies, the VIFU 2000 enables users to research ultrasound meditated drug delivery study, ablation for solid tumor, mechanical and cavitation effect in ex-vivo / in-vivo study. Optimally designed for research laboratories, the VIFU 2000 is a compact and ...

PCL provides a reinforcing structure to load-bearing tissue constructs, including bone grafts and osteochondral plugs developed for in vitro and in vivo studies. It can also provide a temporary scaffold for overhanging ...

BriaCell’s novel, proprietary PKCδ inhibitors have shown activity against multiple RAS transformed tumors. This target has an attractive safety profile based on in vivo studies and knock out mouse studies. PKCδ also has potential activity as an immunotherapeutic by blocking TGFβ signaling. PKCδ inhibitors are ...

Figure 1 shows Computer Generated Thermal Simulation data of the DirectAblate Renal Denervation SystemTM. Figure 2 is histological sample of an in vivo study performed with the DirectAblate Renal Denervation SystemTM. The treatment zone is nearly identical in size and shape to the computer based modeling as identified with NBT viability staining (blue/purple ...

Highly biocompatible GrowDex has been used widely for the culture of primary cells through to iPS and ES cells. Bridging the gap between in vitro and in vivo studies GrowDex can be used for 3D cell culture for spheroid and organoids, in personalised medicine, regenerative medicine, organ-on-a-chip models, high throughput screening, drug release ...

With a powerful combination of high frame rates and advanced image processing, the Vevo 3100 micro-ultrasound imaging system reduces speckle noise and artifacts while preserving and enhancing critical information for small animal in vivo ...

It has been successfully validated against in vivo studies showing excellent correlation with rolling velocities, adhesion patterns, and migratory processes (Lamberti et al 2014, Soroush et al ...

Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; transplantation into normal or diseased systems; cardiac toxicology studies; or cardiovascular developmental ...

BOS-228 is a novel monobactam for infections caused by multidrug-resistant carbapenem-resistant ...

TIB200 is a topical 10% ibuprofen gel for pain relief that utilises Futura's DermaSys® technology. DermaSys® enables ibuprofen to be delivered rapidly and efficiently through the skin. Local application and rapid, efficient absorption translate into a fast onset of action, and the potential for twice-daily ...

The evaluation of wound dressings and medical devices (e.g. skin substitutes) is of great importance to ensure their effectiveness and safety. We can also determine the "mode of action" of these materials. ...

The HC016 platform is a treatment of acute lung injury, based on mesenchymal stem cells derived from adipose tissue (ASC), improved with proprietary Histocell ...

A membrane with outstanding handling1,2 that facilitates bone gain. A resorbable collagen membrane for guided bone regeneration and guided tissue regeneration ...

Myelin Oligodendrocyte Glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (CNS). Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and ...

With our OTF InStrip: technology we are able to work with a wide range of physiologically active substances, the delivery of which we can modify according to the nature of substance and requirements of the partner. The technology gives the advantage to produce products for both human and veterinary ...

The Vevo® 3100 LT Imaging System is FUJIFILM VisualSonics’ entry-level micro-ultrasound product. It is perfectly suited for performing basic preclinical studies while meeting both your research and budgetary needs. The Vevo 3100 LT offers real-time, in vivo physiological information that contributes to understanding biological functions and so much ...

Cebedix & Cebidix-h are an Oral Thin Films using our InStripTM technology with CBD (Canabidiol). InStrip technology allows you to use the full potential of the substances contained in Cebedix, in this case CBD. You will achieve the desired effect from a much smaller dose. And a smaller dose means a smaller toll on the organism. The first effects of Cebedix in the form of a thin, ...