In Vitro Study Equipment & Supplies

Precision Approach to Address the Underlying Cause of Disease: Our second candidate, MuSK-CAART, is designed to treat myasthenia gravis (MG), an autoimmune disease affecting the neuromuscular junction that can lead to motor impairment, muscle weakness, and respiratory ...

A combination therapy consisting of PKC agonists with or without HDAC inhibitors, designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body. HIV Latency: Although highly active antiretroviral therapy (HAART) is undoubtedly a lifesaving therapy for millions of AIDS patients, the persistence of latent HIV-infected cellular ...

Large organoids and tissue models can be grown in vitro in flow-free culture, reducing the time to organoid development while maintaining the properties of a 3D organoid. Organoid scaffolds are laser printed using transplantable hydrogel material allowing for both in vitro studies and transplantation of the same tissues into animal models. ...

Epithelix is offering primary Human Alveolar Pneumocytes, low passage, isolated from biopsies. Alveolar pneumocytes are commonly used for in vitro studies related with pulmonary diseases and chemical ...

This program leverages know-how and capabilities acquired under our previous programs with regard to topical formulation and clinical testing. In preclinical in vitro studies, BX005 was shown to be active against over 90% of strains of S. aureus isolated from the skin of subjects from U.S. and Europe, including antibiotic resistant strains. ...

Epithelix is offering primary Human Small Airway Epithelial Cells (hSAEC), passage 1, isolated from biopsies. They are commonly used for in vitro studies related with pulmonary diseases and chemical testing. They are now a standard for research on asthma, COPD, cancer, cystic fibrosis, bacterial and viral infections. These cells are also a useful tool for the ...

The liver is the main metabolic organ responsible for pathways such as glycolysis, glycogenesis, ureagenesis, as well as amino acid and lipid metabolism. The predominant cells type is the hepatocyte; therefore, cultured human hepatocytes are suited for in vitro metabolism studies. upcyte® Hepatocytes are expanded primary cells, derived from single ...

PCL provides a reinforcing structure to load-bearing tissue constructs, including bone grafts and osteochondral plugs developed for in vitro and in vivo studies. It can also provide a temporary scaffold for overhanging ...

Cytokine production induced by PHA mimics that seen after brisk stimulation of human immune cells by an immunogenic pathogen or an infection. We obtain source material PBMCs from FDA-licensed blood banks. Preclinical data from animal and in vitro studies, as well as biologic data from patients in clinical trials, demonstrate that IRX-2 acts in multiple ways to ...

Get more out of your neuronal cultures and co-cultures with the latest in microfluidic devices from eNUVIO. OMEGA4 devices can be used for in vitro co-culture studies of neurodegeneration, neuromuscular junction (NMJ), nigrostriatal pathway, pain, myelination, or chemotactic factors. In single culture applications, the OMEGA4 can serve as a compartmentalization ...

Each experimental unit consists of one standard sized chamber and one small chamber. OMEGA4-2mini devices can be used for in vitro co-culture studies of neurodegeneration, neuromuscular junction (NMJ), nigrostriatal pathway, pain, myelination, or chemotactic factors. In single culture applications, the OMEGA4-2mini can serve as a compartmentalization tool to ...

Each experimental unit consists of one standard sized chamber and one small chamber. OMEGA4-2mini-2mm devices can be used for in vitro co-culture studies of neurodegeneration, neuromuscular junction (NMJ), nigrostriatal pathway, pain, myelination, or chemotactic factors. In single culture applications, the OMEGA4-2mini-2mm can serve as a compartmentalization ...

Get even more out of your neuronal cultures and co-cultures with the latest in microfluidic devices from eNUVIO. OMEGAACE devices can be used for in vitro triple co-culture studies of neurodegeneration, neuromuscular junction (NMJ), nigrostriatal pathway, pain, myelination, or chemotactic factors. In single culture applications, the OMEGAACE can also serve as a ...

Clinical testing on humans can only begin after a pre-clinical phase, involving laboratory studies (in vitro) and tests on animals, which has shown that the experimental drug is considered safe and effective. However, no animal is sufficiently similar to humans (even genetically modified ones) to make human testing unnecessary. ...

They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize contraction-relaxation cycles of the cardiomyocytes. Cardiomyocytes may be used in various in vitro or in vivo studies; ...

PMC-402 is a monoclonal antibody that targets the human TIE2 that regulated activation, proliferation, and repolarization of Tie2 expressing macrophages, resulting in T cell activation. It binds to TIE2 expressing macrophages that activate T cells in the tumor microenvironment ...

TP-0184 is an investigational inhibitor of activin receptor-like kinase 2 (ALK2) and ALK5 (also known as TGFβR1). This bimodal inhibitor is believed to downregulate multiple TGF-β superfamily signaling pathways and has shown antitumor activity in several ...

TIB200 is a topical 10% ibuprofen gel for pain relief that utilises Futura's DermaSys® technology. DermaSys® enables ibuprofen to be delivered rapidly and efficiently through the skin. Local application and rapid, efficient absorption translate into a fast onset of action, and the potential for twice-daily ...

Scientific advisory meeting held with MHRA confirming the need of a Phase 3 study to support the improved skin permeation including potential superior efficacy claims. Exploring the feasibility of a clinical study to satisfy the Phase 3 requirements for both UK and US approval. Development currently on ...

Bone regeneration is a cellular process that involves the interaction of osteoblasts and stem cells with the surface of a bone graft material. Studies have shown that the bone graft surface structure and morphology can impact how cells interact with a material. The TrelCor advanced bone graft material has a nanosized surface structure and morphology that provides an optimal ...