Forge Biologics, Inc.

Advanced Technologies

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At Forge, our platform approach employs the triple plasmid transfection method – the industry-standard method for manufacturing AAV. This method is bolstered by Forge’s proprietary technologies, our Ignition Cells™ and pEMBR™ adenovirus helper plasmid.

Ignition Cells

  • Clonal HEK293 mammalian suspension cell line
  • Royalty-free license for clients
  • Optimized for robust transient transfection
  • Animal component free
  • Scalable production

pEMBR Adenovirus Helper Plasmid

  • Adenovirus Helper Plasmid
  • Lower cost for production
  • Improved safety profile – removed unnecessary adenoviral elements
  • Forge Biologics intellectual property
  • Available for pipeline use

pEMBR Design Features

pEMBR Yield Comparison

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