Pre-Clinical Equipment & Supplies Near Europe

Bertin Bioreagent offers primary and secondary antibodies for laboratories. As essential tools, they are particularly versatile when properly ...

Carbiotix believes that activity within the gut microbiome is more important than the presence of specific bacteria species. As such, the company focuses on engineering microbiome modulators (proprietary second-generation soluble fibres, isolated bacterial strains, and novel delivery mechanisms) to restore and optimize gut microbiome metabolic processes, and thereby obtain the desired effect ...

Camurus' clinical pipeline represents a healthy mix of in-house and partnered programs from early to late stage development. Our innovative product candidates are designed to address important unmet medical needs, with the potential to make a significant difference in the daily life of patients by improving treatment outcomes, quality of life, and long-term ...

FluidCrysta nanoparticles can resolve bioavailability issues for water and lipid-soluble pharmaceuticals or biodegradation-sensitive drugs, such as peptides and proteins. FluidCrystal nanoparticles are usually water-based and comprise a stable emulsion of nanoparticles with a liquid crystalline structure. Investigational medicinal products based on this technology are administered either ...

2A Pharma’s AAVLP-HER2/Neu peptide vaccine candidate has in laboratory tests been shown to induce antibodies specific to human HER2. In mouse models, regression of breast cancer tumors was observed after vaccination. In a proof-of-principle study carried out at the Medical University of Vienna, Austria, supported by Medigene AG, it was concluded that this vaccine strategy could help to ...

2A Pharma’s anti-amyloid-beta vaccine candidate, AAVLP-Amyloid-β, has in laboratory tests with transgenic mice over-expressing amyloid-beta mutant protein been shown to eliminate amyloid-beta soluble protein, a clear plaque from the cortex and significantly reduce plaque from the hippocampus. It is our hope that the drug candidate can be developed into a treatment for early-stage ...

The CentoPharma platform provides intelligent access to our comprehensive data repository that combines phenotype, genotype and biochemistry information with epidemiological data and clinical information from a global cohort originating from more than 120 countries. Dynamic search criteria enable the targeted compilation of individual customized cohorts based on desired geographical region, ...

An arc with high current density is run over the target material causing it to evaporate and to release titanium atoms, which are ionized and propelled towards the implant. During the process, nitrogen is introduced into the vacuum chamber. The TiN coating is formed when the titanium ions strike the implant surface and, simultaneously, combine with the nitrogen atoms. ...

An arc with high current density is run over the target material causing it to evaporate and to release titanium and niobium atoms, which are ionized and propelled towards the implant. During the process, nitrogen is introduced into the vacuum chamber. The TiNbN coating is formed when the titanium and niobium ions strike the implant surface and, simultaneously, combine with the nitrogen ...

A porous TPS coating is applied on the implants using a vacuum plasma spray process to modify the surface of ceramic implants and thus to make the surface attractive for improved osseointegration. ...

Chosen more often than any other to provide an effective barrier against bacterial transfer and standardize clinical protocols for all patients and care areas. Help enhance safety and efficiency by choosing industry-leading infection control technology. When you choose ICU Medical needlefree IV sets and connectors with patented Clave™ technology, you get an effective barrier against ...

Maintain a needlefree closed system to help minimize exposure to hazardous drugs and comply with USP. Prohibits the escape of hazardous drug or vapor concentrations, Blocks the transfer of environmental contaminants into the system, Eliminates needlestick injuries while minimizing , hazardous drug exposure. With the ChemoLock needlefree CSTD, it has never been easier to keep yourself safe from ...

Daratumumab is a human IgG1k monoclonal antibody (mAb) that binds with high affinity to the CD38 molecule, which is highly expressed on the surface of multiple myeloma cells.1 Daratumumab is being developed by Janssen Biotech, Inc. under an exclusive worldwide license to develop, manufacture and commercialize daratumumab from Genmab. A subcutaneous formulation of daratumumab, DARZALEX ...

GEN3014 (HexaBody®-CD38) is a novel human CD38 monoclonal antibody incorporating Genmab’s HexaBody® technology. In June 2019, Genmab entered into an exclusive worldwide license and option agreement with Janssen Biotech Inc. to develop and commercialize HexaBody®-CD38. In preclinical models of hematological malignancies, HexaBody®-CD38 demonstrated enhanced ...

DuoBody-CD40x4-1BB (GEN1042) is a proprietary bispecific antibody, jointly owned by Genmab and BioNTech, created using Genmab’s DuoBody® technology. It is being co-developed under an agreement in which the companies share all costs and future profits for the product on a 50:50 basis. CD40 and 4-1BB were selected as targets to enhance both dendritic cells (DC) and antigen-dependent ...

Tisotumab Vedotin is an antibody-drug conjugate (ADC) targeted to tissue factor (TF), a protein involved in tumor signaling and angiogenesis.1 It is composed of Genmab’s human monoclonal antibody (mAb) that binds to TF and Seagen’s ADC technology that utilizes a cleavable linker and the cytotoxic drug monomethyl auristatin E (MMAE).1 TF is a transmembrane protein that is the main ...

Ofatumumab is a human monoclonal antibody which targets an epitope in the CD20 molecule encompassing parts of the small and large extracellular ...

Specificity:ABS 004-22 is specific for complement factor C9. ...

The Aidmed One recorder is a portable medical device. It is designed to be worn on the chest by the patient using an attached chest strap and an attached pulse ...

Reliable Identification of SARS-CoV-2-Specific T-Cell Responses. T Cells Take the Lead in COVID-19. A deeper understanding of viral-specific T-cell responses to COVID-19 is needed to explore vaccine responses, long-term immunity, predict patients at risk, and even prepare for the next pandemic. T-cell responses are believed to be important for protection against severe disease through the ...