Pre-Clinical Equipment Supplied In New Jersey

Strong scientific and clinical rationale for LSD1/HDAC6 inhibition in haematological and solid ...

Strong scientific and clinical rationale for novel small molecule PD-L1 ...

CYNK-001 is the only cryopreserved, allogeneic, off-the-shelf, natural killer (NK) cell therapy being developed from placental hematopoietic stem cells as a potential treatment option for various hematologic cancers, solid tumors, and infectious disease. NK cells are a unique class of immune cells, innately capable of targeting cancer cells and interacting with adaptive ...

EXPAREL is indicated for single-dose infiltration in patients aged 6 years and older to produce postsurgical local analgesia and in adults as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia. Safety and efficacy have not been established in other nerve ...

Healthcare professionals and caregivers, including staff in hospitals, assisted living facilities and at-home care settings, need vial boxes with simple instructions and easy storage that protect products and support ease of parenteral drug ...

CYNK-CAR candidates are being developed as allogeneic, off-the-shelf approaches through gene modification of human placental hematopoietic stem cell-derived natural killer (NK) cells. Various CAR constructs against hematological and solid tumor targets are under pre-clinical ...

he CytoSorb therapy* is based on an extracorporeal blood purification procedure that was shown to effectively reduce excessive levels of inflammatory mediators (see “The Adsorber”). This is intended to alleviate the excess systemic inflammatory response (“cytokine storm”) associated with systemic hyperinflammation or septic shock. Thus, the life-threatening complications ...

Our lead drug candidate, ENA-001, is a patent-protected new chemical entity (NCE) beginning additional clinical trials during the fourth quarter of 2021. With its novel mechanism-of-action and demonstrated safety and efficacy, it holds the potential of dramatically improving the lives of those impacted by several life threatening conditions including drug overdose, post-operative respiratory ...

RNase Inhibitor, Mammalian specifically inhibits RNases A, B and C. It inhibits RNases by binding noncovalently in a 1:1 ratio with high affinity. It is not effective against RNase 1, RNase T1, S1 Nuclease, RNase H or RNase from Aspergillus. In addition, no inhibition of polymerase activity is observed when RNase Inhibitor is used with Taq DNA Polymerase, AMV or M-MuLV Reverse Transcriptases, or ...

The embedding center that you choose plays a critical role in the performance of your lab. Throughput, ease of use, ergonomics and performance are all key factors for your lab in order to run efficiently and flawlessly. The Avantik EM8 Embedding Center is an integral part of creating a lab. The modular design allows for easy and customized setup of the hot and cold plate surfaces. The control ...

We are developing CYNK-101 as a combination treatment for multiple cancer indications. CYNK-101 is manufactured from a specific type of immune cell, NK cells, that we extract from postpartum placentas and then genetically engineer to increase cell killing activity when introduced together with an antibody-based anti-cancer treatment. ...

The Linistain Automatic Slide Stainer is a dependable and economical way to automate staining; it uses a conveyer to prepare consistently stained slides. The supply and drain ports are located at the rear and on the left as you face the instrument. The accessory stands substantially improve the instrument drainage. A dedicated water shut-off is recommended for the water supply leading to the ...

Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol is 1000 times more selective for ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50 >>10 μM). Falnidamol is a pyrimidine-pyrimidine compound with anti-cancer ...

Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human ...

TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma ...

Highly absorbent and versatile biocomposite matrices that can be easily cut and sized in either the dry or hydrated state and are fully resorbed during bone remodeling. They are osteoconductive and when mixed with autogenous bone marrow become osteoinductive and ...

Synthetic nerve guides are indicated for reconstruction of peripheral nerve discontinuities up to 20 ...

Indirect Immunofluorescence Assay is a qualitative or semi-quantitative assay for the in vitro diagnostic detection of Anti-nuclear Antibodies in human serum on human epithelial cells (HEp2). The test is intended as an aid in the diagnosis of SLE and connective tissue ...

Indications: Barhemsys is a selective dopamine-2 (D2) and dopamine-3 (D3) receptor antagonist indicated in adults for: prevention of postoperative nausea and vomiting (PONV), either alone or in combination with an antiemetic of a different class treatment of PONV in patients who have received antiemetic prophylaxis with an agent of a different class or have not received ...

In terms of requirements and restrictions, few industries are as demanding as the world of clinical trials. We have dedicated years to developing breakthrough packaging solutions that have become widely accepted by some of the most respected names in the pharmaceutical ...