Medical Specialties Equipment Supplied In Maryland

ES104 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. VEGF also plays an important role in creating an immune suppressive TME. Pre-clinical and early clinical data of ES104 show that blocking both pathways provides robust ...

MEDI+SIGN digital patient room whiteboard display replaces traditional dry-erase boards in hospital patient rooms. This patient and family facing digital solution solves many problems that can arise with the traditional whiteboard. Information is continuously updated as providers revise the patient’s electronic health records (EHRs), healthcare acronyms are translated for easy patient ...

The DxNow CSI-Q™ cartridge is designed to aid the forensic DNA analyst to rapidly identify the most probative sample(s) in forensic DNA casework to submit for further DNA Analysis. CSI-Q is based on the same scientific principles of the innovative NGDE™ technology. Sexual assault evidence samples will be extracted by standard laboratory procedure and an aliquot will be loaded on the ...

BioFactura is developing a Marburg therapeutic in close collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). Marburg virus (MARV) was first described in 1967 as the causative agent of a hemorrhagic fever illness that occurred in laboratory workers at a primate facility in Germany and Yugoslavia. Since its discovery, marburgviruses have caused at ...

Automatically detect flow compromise with ultrasound. EchoSure helps identify issues early and quickly with automated realtime, definitive, visual and quantitative blood flow monitoring. Help avoid false-positives with real-time visualization of blood flow through the vein and artery. ...

With a mortality rate of over 30%, smallpox is one of the most dangerous biological threats. It is person-to-person airborne communicable, highly contagious and exhibits a long pre-symptomatic phase (12-14 days) allowing undetectable spread worldwide. While smallpox was declared eradicated in 1980 by the World Health Organization after an extensive vaccination campaign, the threat of bioterrorism ...

The Hemafuse is a handheld, mechanical device for intraoperative autotransfusion of blood collected from an internal hemorrhage, meant to replace or augment donor blood in emergency ...

Mucopolysaccharidosis type 1 (MPS 1) is a rare lysosomal storage disease that is caused by mutations in IDUA, the gene that encodes the alpha-L-iduronidase (IDUA) enzyme. These mutations cause the misfolding and dysfunction of IDUA, which leads to the toxic buildup of large sugars in the bone, cartilage, cornea, heart and central nervous system (CNS). There is currently no cure for these ...

ES004 is a potentially best-in-class antibody targeting pan-allele signal-regulatory protein alpha (SIRPα). SIRPα is an inhibitory receptor expressed only on myeloid cells and dendritic cells. Binding of CD47 to SIRPα delivers a “don’t eat me” signal to suppress phagocytosis. Tumor cells frequently overexpress CD47 to evade macrophage-mediated destruction. To ...

The most widely recognized method of removing cells in use today is “immersion decellularization” in which a tissue or organ is soaked in strong detergent which diffuses from the outer surface inward, and then back out once the cells are dissolved which is limited to a few millimeters. The end result is a partially degraded scaffold with a compromised vascular network and an outer ...

VAXCHORA is a vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1 in adults 18 through 64 years of age traveling to cholera-affected ...

Andrographolide is an extract from the stem and leaves of the andrographis paniculata. Andrographolide is an extremely bitter substance, and a natural bitterant. The plant is grown for medicinal purposes in China and India, and is being used as a homeopathic treatment for stomach disorders in the United States. Andrographolide has been shown to be effective against certain cancers and is a ...

Orenitram is a prostacyclin mimetic indicated for treatment of pulmonary arterial hypertension (PAH; WHO Group 1), to delay disease progression and to improve exercise capacity. The studies that established effectiveness included predominately patients with WHO functional class II-III symptoms and etiologies of idiopathic or heritable PAH (66%) or PAH associated with connective tissue disease ...

The Maxim Swift HIV Recent Infection Assay (RIA) is a single use qualitative immunoassay to detect the circulating antibodies to Human Immunodeficiency Virus Type 1 (HIV-1), Type 2 (HIV-2) and distinguish between recent and long-term infection in HIV-1/2. The assay is a point of care (POC) test intended for use with blood or serum/ plasma specimens. The Maxim Swift™ HIV RIA uses US CDC ...

A Severe Malaria Treatment, Vital for the US Healthcare Community. No FDA-approved injectable malaria medication has been available in the US since IV quinidine was discontinued in early 2019. Artesunate for Injection fills this ...

Harmony Practice Management solution is designed to enhance efficiencies, drive up revenue, and improve patient care. Our system schedules, bills and communicates with your patients, and helps you take control of your practice with less investment of resources. ...

Building upon 30 years of advances in artificial intelligence, device development and medical simulation derived hardware and software integration, the 3CPM Company pioneered future advancements in Electrogastrography and Electroviscerography embodied in the Tricorder-3L. Miniaturization of hardware components coupled with evidence-based AI-driven software diagnostics and interpretation gave rise ...

OX40, also known as CD134, is a member of the tumor necrosis factor (TNF) receptor family and is an important co-stimulator of T cell responses. Typically for TNF receptor family members, 3 molecules of OX40 bind to the trimeric OX40 ligand-protein, activating downstream NF-κB, PI3K, and AKT pathways, which lead to increased cytokine production. Activation of OX40 enhances T-cell expansion, ...

LAG3 is an immune checkpoint receptor known to suppress T cell activation. We designed ES005 to block LAG3 ligands, including MHC class II and FGL1. Through unique epitope binding, ES005 is able to recognize human LAG3 with high affinity. In preclinical studies, ES005 inhibited tumor growth both as a monotherapy and in combination with a PD-1 ...

BC Sera Dx Immunoassay test panel for detection of the presence of breast cancer in women. In the development pipeline are an Ovarian, OV Sera Dx, and Lung, LG Sera Dx, cancer detection test ...