Medical Drugs Equipment Supplied In Massachusetts

Membrane holder, stainless steel syringe filter type. Available in stainless steel and polypropylene with luer fittings for use with a standard syringe. The holders are designed for the quick and easy clarification, sterilization*, and removal of particulates from small volume samples, typically for HPLC applications. The holders contain PTFE gaskets and O-rings and allow the membrane to be ...

VOR33 is our lead eHSC product candidate designed to replace the standard of care in transplant settings. Once the VOR33 cells have engrafted, we believe that patients can be treated with anti-CD33 therapies, such as Mylotarg or VCAR33, with limited on-target toxicity, leading to durable anti-tumor activity and potential cures. In preclinical studies, we have observed that the removal of CD33 ...

ImmTOR has significant potential to mitigate unwanted immune responses and induce AAV-specific tolerance to enable redosing of gene therapies. ImmTOR has the potential to administer multiple low doses to achieve therapeutic benefit without risk of overdosing, the ability to treat patients typically excluded from these treatments and is a novel approach to treating systemic diseases ...

We have reimagined ultrasound as a simple and effective delivery platform, which acts on the therapeutic molecules themselves, achieving ultra-rapid, formulation-independent drug delivery. This enables us to “push” virtually any therapeutic class, including temperamental molecules, like nucleic acids, directly into cells with astounding efficacy and accuracy, affecting historically ...

EDIT-301 is an experimental cell therapy medicine under investigation for the treatment of severe sickle cell disease (SCD) and transfusion-dependent beta thalassemia (TDT). EDIT-301 consists of patient-derived CD34+ hematopoietic stem and progenitor cells edited at the gamma globin gene (HBG1 and HBG2) promoters, where naturally occurring fetal hemoglobin (HbF) inducing mutations reside, by a ...

Highlights: Micro injection-molded parts in millions of variations. Components weighing under 0.00004 oz (0.001g). Thin-wall molding with wall thicknesses as thin as 0.006 in (0.15 mm). Components molded consistently and with extreme precision. Expert, in-house mold building and decades of ...

Uses: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active ...

Uses: Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active ...

DC Bead is an embolic Drug-Eluting Bead capable of loading and releasing in a controlled manner chemotherapeutic agents. DC Bead is used in trans-arterial chemoembolisation (TACE). This is a minimally invasive (non-surgical) procedure performed by an interventional ...

RTX-321 is an allogeneic, off-the-shelf artificial antigen presenting cell (aAPC) therapy product candidate that is engineered to induce a tumor-specific immune response by expanding antigen-specific T cells. RTX-321 expresses hundreds of thousands of copies of an HPV peptide antigen bound to major histocompatibility complex (MHC) class I proteins, the costimulatory molecule 4-1BBL and the ...

The DiagnosysFST®, Full-field Stimulus Threshold, module uses the ColorDome™or ColorFlash™ stimulator. It measures the sensitivity of the visual field by testingfor the lowest luminance flash which elicits a visual sensation perceived by thesubject. The test is run on either dark- or light-adapted patients for one or botheyes in an automated routine to measure a reliable ...

Tafasitamab (MOR208) is a humanized FC-modified CD19 targeting immunotherapy in clinical development for the treatment of B cell malignancies. CD19 is broadly expressed on the surface of B cells. It is therefore considered as a potential target for the treatment of B cell malignancies, such as non-Hodgkin’s lymphoma (NHL), including diffuse large B cell lymphoma (DLBCL), indolent lymphomas ...

Pirouette Medical has developed and is bringing to market a revolutionary auto-injector. Auto-injectors are automated injection systems designed to allow self- or caregiver- administration; even by untrained individuals. Pirouette is initially developing an epinephrine auto-injector (EAI), which is used for the emergency treatment of severe allergic reactions. Existing EAIs leave patients ...

ALVR108 is an investigational allogeneic, off-the-shelf VST therapy designed to treat human herpesvirus-8 (HHV-8). ...

SER-155 is an investigational, oral, rationally designed, fermented microbiome therapeutic designed to reduce the incidence of gastrointestinal infections, bacteremia, and graft versus host disease (GvHD) in immunocompromised patients, including patients receiving allogeneic hematopoietic stem cell transplantation ...

Posoleucel targets five devastating viral pathogens: BK virus (BKV), Cytomegalovirus (CMV), Adenovirus (AdV), Epstein-Barr Virus (EBV), and Human Herpesvirus 6 (HHV-6), and has the potential to transform care for transplant recipients. ...

Wearable and nonwearable auto-injectors. Syringes. Insulin pens. Intraosseous device ...

Immunosynthen is our novel immunostimulatory ADC platform designed to take ADCs beyond traditional cytotoxic drugs to targeted stimulation of the innate immune system. Through the safe and efficient delivery of a novel immunomodulatory STING agonist, ADCs created with our Immunosynthen platform have the potential to address the challenges of efficacy, delivery and tolerability. Stimulator of ...

This device is supported by an ongoing NIH grant and potential for follow-on ...

The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to assess the overall ...