Viscoll

When developing a matrix for matrix-assisted cell transplantation, researchers inevitably face the problem of choosing a biopolymeric matrix that must ensure the survival of the cells contained in it before and after their introduction into the living organism. Polymeric materials serving as the basis for the formation of such a matrix structure must be compatible with both the cells included in them and in the living tissues. They should slowly decompose in the body without turning into harmful components and gradually being replaced by an extracellular matrix synthesized by the organism`s own cells. Such polymeric materials, as well as the products of their decomposition, should not be immunogenic. Among the large number of natural and synthetic polymers, native highly purified collagen is biocompatible and does not cause a virus-specific immune response, as is the characteristic for other proteins and biopolymers.