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Forge Biologics, Inc.
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4 products found

Forge Biologics, Inc. Products

  • Model FBX-101 - Galactosylceramidase (GALC) Gene for Krabbe Disease

    Model FBX-101 - Galactosylceramidase (GALC) Gene for Krabbe Disease

    Krabbe disease is a devastating neurodegenerative disease affecting about 1 -2.5 in 100,000 people in the U.S. and is inherited in an autosomal recessive manner. Krabbe disease is caused by loss-of-function mutations in the galactosylceramidase (GALC) gene, a lysosomal enzyme responsible for the breakdown of certain types of lipids such as psychosine. Without functional GALC, psychosine accumulates to toxic levels in cells. The psychosine toxicity is most ...

  • Ignition Cells

    Ignition Cells

    Royalty-free license for clients; Clonal HEK293 mammalian suspension cell line; Optimized for robust transient transfection; Animal component free; Scalable ...

  • pEMBR - Adenovirus Helper Plasmid

    pEMBR - Adenovirus Helper Plasmid

    Lower cost for production; Improved safety profile – removed unnecessary adenoviral elements; Forge Biologics intellectual property; Available for pipeline ...

  • Technology

  • Advanced Technologies

    Advanced Technologies

    At Forge, our platform approach employs the triple plasmid transfection method – the industry-standard method for manufacturing AAV. This method is bolstered by Forge’s proprietary technologies, our Ignition Cells™ and pEMBR™ adenovirus helper ...